February was first proclaimed as American Heart Month in 1964. Since then, its 28 (or 29) days have served as an opportunity to encourage people to focus on their cardiovascular health.
The International Space Station serves as a platform for a variety of ongoing research on human health, including how different body systems adapt to weightlessness. This research includes assessing cardiovascular health in astronauts during and after spaceflight and other studies using models of the cardiovascular system, such as tissue cultures. The goal of this work is to help promote heart health for humans in space and everyone on Earth. For this Heart Month, here is a look at some of this spaceflight research
Microgravity exposure is known to cause changes in cardiovascular function. Engineered Heart Tissues assessed these changes using 3D cultured cardiac tissues that model the behavior of actual heart tissues better than traditional cell cultures. When exposed to weightlessness, these “heart-on-a-chip” cells behaved in a manner similar to aging on Earth. This finding suggests that these engineered tissues can be used to investigate the effects of space radiation and long-duration spaceflight on cardiac function. Engineered tissues also could support development of measures to help protect crew members during a mission to Mars. Advanced 3D culture methodology may inform development of strategies to prevent and treat cardiac diseases on Earth as well.
For decades, human research in space has focused on professional and government-agency astronauts, but commercial spaceflight opportunities now allow more people to participate in microgravity research. Cardioprotection Ax-1 analyzed cardiovascular and general health in private astronauts on the 17-day Axiom-1 mission.
The study found that 14 health biomarkers related to cardiac, liver, and kidney health remained within normal ranges during the mission, suggesting that spaceflight did not significantly affect the health of the astronaut subjects. This study paves the way for monitoring and studying the effects of spaceflight on private astronauts and developing health management plans for commercial space providers.
Vascular Echo, an investigation from CSA (Canadian Space Agency), examined blood vessels and the heart using a variety of tools, including ultrasound. A published study suggests that 3D imaging technology might better measure cardiac and vascular anatomy than the 2D system routinely used on the space station. The research team also developed a probe for the ultrasound device that better directs the beam, making it possible for someone who is not an expert in sonography to take precise measurements. This technology could help astronauts monitor heart health and treat cardiovascular issues on a long-duration mission to the Moon or Mars. The technology also could help patients on Earth who live in remote locations, where an ultrasound operator may not always be available.
As part of exploring ways to keep astronauts healthy on missions to the Moon and Mars, NASA is conducting a suite of space station studies called CIPHER that looks at the effects of spaceflight lasting up to a year. One CIPHER study, Vascular Calcium, examines whether calcium lost from bone during spaceflight might deposit in the arteries, increasing vessel stiffness and contributing to increased risk of future cardiovascular disease. Astronaut volunteers provide blood and urine samples and undergo ultrasound and high-resolution scans of their bones and arteries for this investigation. Another CIPHER study, Coronary Responses, uses advanced imaging tests to measure heart and artery response to spaceflight.
These studies will help scientists determine whether spaceflight accelerates narrowing and stiffening of the arteries, known as atherosclerosis, or increases the risk of atrial fibrillation, a rapid and irregular heartbeat seen in middle-aged adults. This work also could help identify potential biomarkers and early warning indicators of cardiovascular disease.
Melissa Gaskill
International Space Station Research Communications Team
Johnson Space Center
2 min read
We’ve been talking about this for 2,000 years. Aristotle mentions it. And in our own time, scientists are designing experiments to figure out exactly what’s going on. But there’s no consensus yet.
Here’s what we do know.
The atmosphere isn’t magnifying the Moon. If anything, atmospheric refraction squashes it a little bit. And the Moon’s not closer to us at the horizon. It’s about 1.5 percent farther away. Also, it isn’t just the Moon. Constellations look huge on the horizon, too.
One popular idea is that this is a variation on the Ponzo illusion. Everything in our experience seems to shrink as it recedes toward the horizon — I mean clouds and planes and cars and ships. But the Moon doesn’t do that. So our minds make up a story to reconcile this inconsistency. Somehow the Moon gets bigger when it’s at the horizon. That’s one popular hypothesis, but there are others. And we’re still waiting for the experiment that will convince everyone that we understand this.
So why does the Moon look larger on the horizon? We don’t really know, but scientists are still trying to figure it out.
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A bouquet of thousands of stars in bloom has arrived. This composite image contains the deepest X-ray image ever made of the spectacular star forming region called 30 Doradus.
By combining X-ray data from NASA’s Chandra X-ray Observatory (blue and green) with optical data from NASA’s Hubble Space Telescope (yellow) and radio data from the Atacama Large Millimeter/submillimeter Array (orange), this stellar arrangement comes alive.
Otherwise known as the Tarantula Nebula, 30 Dor is located about 160,000 light-years away in a small neighboring galaxy to the Milky Way known as the Large Magellanic Cloud (LMC). Because it one of the brightest and populated star-forming regions to Earth, 30 Dor is a frequent target for scientists trying to learn more about how stars are born.
With enough fuel to have powered the manufacturing of stars for at least 25 million years, 30 Dor is the most powerful stellar nursery in the local group of galaxies that includes the Milky Way, the LMC, and the Andromeda galaxy.
The massive young stars in 30 Dor send cosmically strong winds out into space. Along with the matter and energy ejected by stars that have previously exploded, these winds have carved out an eye-catching display of arcs, pillars, and bubbles.
A dense cluster in the center of 30 Dor contains the most massive stars astronomers have ever found, each only about one to two million years old. (Our Sun is over a thousand times older with an age of about 5 billion years.)
This new image includes the data from a large Chandra program that involved about 23 days of observing time, greatly exceeding the 1.3 days of observing that Chandra previously conducted on 30 Dor. The 3,615 X-ray sources detected by Chandra include a mixture of massive stars, double-star systems, bright stars that are still in the process of forming, and much smaller clusters of young stars.
There is a large quantity of diffuse, hot gas seen in X-rays, arising from different sources including the winds of massive stars and from the gas expelled by supernova explosions. This data set will be the best available for the foreseeable future for studying diffuse X-ray emission in star-forming regions.
The long observing time devoted to this cluster allows astronomers the ability to search for changes in the 30 Dor’s massive stars. Several of these stars are members of double star systems and their movements can be traced by the changes in X-ray brightness.
A paper describing these results appears in the July 2024 issue of The Astrophysical Journal Supplement Series. NASA’s Marshall Space Flight Center manages the Chandra program. The Smithsonian Astrophysical Observatory’s Chandra X-ray Center controls science operations from Cambridge, Massachusetts, and flight operations from Burlington, Massachusetts.
Read more from NASA’s Chandra X-ray Observatory.
Learn more about the Chandra X-ray Observatory and its mission here:
Visual Description
This release features a highly detailed composite image of a star-forming region of space known as 30 Doradus, shaped like a bouquet, or a maple leaf.
30 Doradus is a powerful stellar nursery. In 23 days of observation, the Chandra X-ray telescope revealed thousands of distinct star systems. Chandra data also revealed a diffuse X-ray glow from winds blowing off giant stars, and X-ray gas expelled by exploding stars, or supernovas.
In this image, the X-ray wind and gas takes the shape of a massive purple and pink bouquet with an extended central flower, or perhaps a leaf from a maple tree. The hazy, mottled shape occupies much of the image, positioned just to our left of center, tilted slightly to our left. Inside the purple and pink gas and wind cloud are red and orange veins, and pockets of bright white light. The pockets of white light represent clusters of young stars. One cluster at the heart of 30 Doradus houses the most massive stars astronomers have ever found.
The hazy purple and pink bouquet is surrounded by glowing dots of green, white, orange, and red. A second mottled purple cloud shape, which resembles a ring of smoke, sits in our lower righthand corner.
Megan Watzke
Chandra X-ray Center
Cambridge, Mass.
617-496-7998
mwatzke@cfa.harvard.edu
Lane Figueroa
Marshall Space Flight Center, Huntsville, Alabama
256-544-0034
lane.e.figueroa@nasa.gov
President Donald Trump's nominees to run the National Institutes of Health (NIH) and the Food and Drug Administration (FDA) are part of a group of scientists who just launched a new research journal focused on spurring scientific discourse and combating "gatekeeping" in the medical research community.
The journal, titled the Journal of the Academy of Public Health (JAPH), includes an editorial board consisting of several scientists who complained of facing censorship during the COVID-19 pandemic.
JAPH's co-founders include Martin Kulldorff, a former Harvard Medical School professor who is a founding fellow at Hillsdale College's Academy for Science and Freedom, and Dr. Jay Bhattacharya, a professor of health policy at Stanford University who is also Trump's nominee to be the next NIH director. Kulldorff and Bhattacharya became known during the pandemic for authoring The Great Barrington Declaration, which sought to challenge the broader medical community's prevailing notions about COVID-19 mitigation strategies, arguing that – in the long run – the lockdowns that people were facing would do more harm than good.
Dr. Marty Makary, a surgeon and public policy researcher at Johns Hopkins University, who is Trump's nominee to be the next director of the FDA, is on the journal's editorial board as well.
JAPH is adopting a novel approach by publishing peer reviews of prominent studies from other journals that do not make their peer reviews publicly available. The effort is aimed at spurring scientific discourse, Kulldorff said in a paper outlining the purposes of the journal's creation.
The journal will also seek to promote "open access" by making all of its work available to everyone in the public without a paywall, he said, and the journal's editorial leadership will allow all scientists within its network to "freely publish all their research results in a timely and efficient manner," to prevent any potential "gatekeeping."
"Scientific journals have had enormous positive impact on the development of science, but in some ways, they are now hampering rather than enhancing open scientific discourse," Kulldorff said. "After reviewing the history and current problems with journals, a new academic publishing model is proposed – it embraces open access and open rigorous peer review, it rewards reviewers for their important work with honoraria and public acknowledgment and it allows scientists to publish their research in a timely and efficient manner without wasting valuable scientist time and resources."
Kulldorff, Bhattacharya, Makary and others on the new journal's leadership team have complained that their views about the COVID-19 pandemic were censored. These were views that were often contrary to the prevailing ideas put forth by the broader medical community at the time, which related to topics such as vaccine efficacy, natural immunity, lockdowns and more.
"Big tech censored the [sic] all kinds of science on natural immunity," Makary said in testimony to Congress following the pandemic. During his testimony, Makary also shared how one of his own studies at Johns Hopkins during the pandemic that promoted the effectiveness of natural immunity, which one scientific journal listed as its third most discussed study in 2022, "was censored."
"Because of my views on COVID-19 restrictions, I have been specifically targeted for censorship by federal government officials," Bhattacharya added in his own testimony to Congress the same year.
Kulldorff, who has also complained about censorship of his views on COVID-19, argued he was asked to leave his medical professorship at Harvard that he held since 2003, for "clinging to the truth" in his opposition to COVID-19 lockdowns and vaccine mandates.
CONSERVATIVE LAW FIRM LAUNCHES PROBE INTO FIVE MAJOR UNIVERSITIES FOR ALLEGED ‘CENSORSHIP REGIME’
"The JAPH will ensure quality through open peer-review, but will not gatekeep new and important ideas for the sake of established orthodoxies," Andrew Noymer, JAPH's incoming editor-in-chief told Fox News Digital.
"To pick one example, in my own sub-field of infectious disease epidemiology, we have in the past few years seen too little published scholarship on the origins of SARS-CoV-2, the virus that causes COVID. Academic publishing as it exists today is too often concerned with preservation of what we think we know, too often to the detriment of new ideas."
Bhattacharya and Makary did not wish to comment on this article.
Astronomers may have discovered a scrawny star bolting through the middle of our galaxy with a planet in tow. If confirmed, the pair sets a new record for the fastest-moving exoplanet system, nearly double our solar system’s speed through the Milky Way.
The planetary system is thought to move at least 1.2 million miles per hour, or 540 kilometers per second.
“We think this is a so-called super-Neptune world orbiting a low-mass star at a distance that would lie between the orbits of Venus and Earth if it were in our solar system,” said Sean Terry, a postdoctoral researcher at the University of Maryland, College Park and NASA’s Goddard Space Flight Center in Greenbelt, Maryland. Since the star is so feeble, that’s well outside its habitable zone. “If so, it will be the first planet ever found orbiting a hypervelocity star.”
A paper describing the results, led by Terry, was published in The Astronomical Journal on February 10.
The pair of objects was first spotted indirectly in 2011 thanks to a chance alignment. A team of scientists combed through archived data from MOA (Microlensing Observations in Astrophysics) – a collaborative project focused on a microlensing survey conducted using the University of Canterbury Mount John Observatory in New Zealand — in search of light signals that betray the presence of exoplanets, or planets outside our solar system.
Microlensing occurs because the presence of mass warps the fabric of space-time. Any time an intervening object appears to drift near a background star, light from the star curves as it travels through the warped space-time around the nearer object. If the alignment is especially close, the warping around the object can act like a natural lens, amplifying the background star’s light.
In this case, microlensing signals revealed a pair of celestial bodies. Scientists determined their relative masses (one is about 2,300 times heavier than the other), but their exact masses depend on how far away they are from Earth. It’s sort of like how the magnification changes if you hold a magnifying glass over a page and move it up and down.
“Determining the mass ratio is easy,” said David Bennett, a senior research scientist at the University of Maryland, College Park and NASA Goddard, who co-authored the new paper and led the original study in 2011. “It’s much more difficult to calculate their actual masses.”
The 2011 discovery team suspected the microlensed objects were either a star about 20 percent as massive as our Sun and a planet roughly 29 times heavier than Earth, or a nearer “rogue” planet about four times Jupiter’s mass with a moon smaller than Earth.
To figure out which explanation is more likely, astronomers searched through data from the Keck Observatory in Hawaii and ESA’s (European Space Agency’s) Gaia satellite. If the pair were a rogue planet and moon, they’d be effectively invisible – dark objects lost in the inky void of space. But scientists might be able to identify the star if the alternative explanation were correct (though the orbiting planet would be much too faint to see).
They found a strong suspect located about 24,000 light-years away, putting it within the Milky Way’s galactic bulge — the central hub where stars are more densely packed. By comparing the star’s location in 2011 and 2021, the team calculated its high speed.
But that’s just its 2D motion; if it’s also moving toward or away from us, it must be moving even faster. Its true speed may even be high enough to exceed the galaxy’s escape velocity of just over 1.3 million miles per hour, or about 600 kilometers per second. If so, the planetary system is destined to traverse intergalactic space many millions of years in the future.
“To be certain the newly identified star is part of the system that caused the 2011 signal, we’d like to look again in another year and see if it moves the right amount and in the right direction to confirm it came from the point where we detected the signal,” Bennett said.
“If high-resolution observations show that the star just stays in the same position, then we can tell for sure that it is not part of the system that caused the signal,” said Aparna Bhattacharya, a research scientist at the University of Maryland, College Park and NASA Goddard who co-authored the new paper. “That would mean the rogue planet and exomoon model is favored.”
NASA’s upcoming Nancy Grace Roman Space Telescope will help us find out how common planets are around such speedy stars, and may offer clues to how these systems are accelerated. The mission will conduct a survey of the galactic bulge, pairing a large view of space with crisp resolution.
“In this case we used MOA for its broad field of view and then followed up with Keck and Gaia for their sharper resolution, but thanks to Roman’s powerful view and planned survey strategy, we won’t need to rely on additional telescopes,” Terry said. “Roman will do it all.”
Download additional images and video from NASA’s Scientific Visualization Studio.
By Ashley Balzer
NASA’s Goddard Space Flight Center, Greenbelt, Md.
Media contact:
Claire Andreoli
NASA’s Goddard Space Flight Center, Greenbelt, Md.
301-286-1940
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