NASA and its international partners have hosted research experiments and fostered collaboration aboard the International Space Station for over 25 years. More than 4,000 investigations have been conducted, resulting in over 4,400 research publications with 361 in 2024 alone. Space station research continues to advance technology on Earth and prepare for future space exploration missions.

Below is a selection of scientific results that were published over the past year. For more space station research achievements and additional information about the findings mentioned here, check out the 2024 Annual Highlights of Results:

• Full Report (PDF)
• Station Research Results website (with extra features)

Making stronger cement

NASA’s Microgravity Investigation of Cement Solidification (MICS) observes the hydration reaction and hardening process of cement paste on the space station. As part of this experiment, researchers used artificial intelligence to create 3D models from 2D microscope images of cement samples formed in microgravity. Characteristics such as pore distribution and crystal growth can impact the integrity of any concrete-like material, and these artificial intelligence models allow for predicting internal structures that can only be adequately captured in 3D. Results from the MICS investigation improve researchers’ understanding of cement hardening and could support innovations for civil engineering, construction, and manufacturing of industrial materials on exploration missions.

Creating Ideal Clusters

The JAXA (Japan Aerospace Exploration Agency) Colloidal Clusters investigation uses the attractive forces between oppositely charged particles to form pyramid-shaped clusters. These clusters are a key building block for the diamond lattice, an ideal structure in materials with advanced light-manipulation capabilities. Researchers immobilized clusters on the space station using a holding gel with increased durability. The clusters returned to Earth can scatter light in the visible to near-infrared range used in optical and laser communications systems. By characterizing these clusters, scientists can gain insights into particle aggregation in nature and learn how to effectively control light reflection for technologies that bend light, such as specialized sensors, high-speed computing components, and even novel cloaking devices.

Controlling Bubble Formation

NASA’s Optical Imaging of Bubble Dynamics on Nanostructured Surfaces studies how different types of surfaces affect bubbles generated by boiling water on the space station. Researchers found that boiling in microgravity generates larger bubbles and that bubbles grow about 30 times faster than on Earth. Results also show that surfaces with finer microstructures generate slower bubble formation due to changes in the rate of heat transfer. Fundamental insights into bubble growth could improve thermal cooling systems and sensors that use bubbles.

Evaluating Cellular Responses to Space

The ESA (European Space Agency) investigation Cytoskeleton attempts to uncover how microgravity impacts important regulatory processes that control cell multiplication, programmed cell death, and gene expression. Researchers cultured a model of human bone cells and identified 24 pathways that are affected by microgravity. Cultures from the space station showed a reduction of cellular expansion and increased activity in pathways associated with inflammation, cell stress, and iron-dependent cell death. These results help to shed light on cellular processes related to aging and the microgravity response, which could feed into the development of future countermeasures to help maintain astronaut health and performance.

Improving Spatial Awareness

The CSA (Canadian Space Agency) investigation Wayfinding investigates the impact of long-duration exposure to microgravity on the orientation skills in astronauts. Researchers identified reduced activity in spatial processing regions of the brain after spaceflight, particularly those involved in visual perception and orientation of spatial attention. In microgravity, astronauts cannot process balance cues normally provided by gravity, affecting their ability to perform complex spatial tasks. A better understanding of spatial processes in space allows researchers to find new strategies to improve the work environment and reduce the impact of microgravity on the spatial cognition of astronauts.

Monitoring low Earth orbit

The Roscomos-ESA-Italian Space Agency investigation Mini-EUSO (Multiwavelength Imaging New Instrument for the Extreme Universe Space Observatory) is a multipurpose telescope designed to examine light emissions entering Earth’s atmosphere. Researchers report that Mini-EUSO data has helped to develop a new machine learning algorithm to detect space debris and meteors that move across the field of view of the telescope. The algorithm showed increased precision for meteor detection and identified characteristics such as rotation rate. The algorithm could be implemented on ground-based telescopes or satellites to identify space debris, meteors, or asteroids and increase the safety of space activities.

For more space station research achievements and additional information about the findings mentioned here, check out the 2024 Annual Highlights of Results.

Destiny Doran

International Space Station Research Communications Team

Johnson Space Center

NASA will provide live launch and docking coverage of a Roscosmos cargo spacecraft delivering approximately three tons of food, fuel, and supplies for the crew aboard the International Space Station.

The unpiloted Roscosmos Progress 91 spacecraft is scheduled to launch at 4:24 p.m. EST, Thursday, Feb. 27 (2:24 a.m. Baikonur time, Friday, Feb. 28), on a Soyuz rocket from the Baikonur Cosmodrome in Kazakhstan.

Live launch coverage will begin at 4 p.m. on NASA+. Learn how to watch NASA content through a variety of platforms, including social media.

After a two-day in-orbit journey to the station, the spacecraft will dock autonomously to the aft port of the Zvezda service module at 6:03 p.m. Saturday, March 1. NASA’s rendezvous and docking coverage will begin at 5:15 p.m. on NASA+.

The Progress 91 spacecraft will remain docked to the space station for approximately six months before departing for re-entry into Earth’s atmosphere to dispose of trash loaded by the crew.

The International Space Station is a convergence of science, technology, and human innovation that enables research not possible on Earth. For more than 24 years, NASA has supported a continuous U.S. human presence aboard the orbiting laboratory, through which astronauts have learned to live and work in space for extended periods of time. The space station is a springboard for developing a low Earth economy and NASA’s next great leaps in exploration, including missions to the Moon under Artemis and, ultimately, human exploration of Mars.

Get breaking news, images and features from the space station on Instagram, Facebook, and X.

Learn more about the International Space Station, its research, and its crew, at:

https://www.nasa.gov/station

-end-

Claire O’Shea
Headquarters, Washington
202-358-1100
claire.a.o’shea@nasa.gov

Sandra Jones
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov

Improving space-based pharmaceutical research

Researchers found differences in the stability and degradation of the anti-Covid drug Remdesivir in space and on Earth on its first research flight, but not on a second. This highlights the need for more standardized procedures for pharmaceutical research in space.

Long-term stability of drugs is critical for future space missions. Because multiple characteristics of spaceflight could influence chemical stability, the scientists repeated their experiment under circumstances as nearly identical as possible. This research used Kirara, a temperature-controlled incubator developed by JAXA (Japan Aerospace Exploration Agency) for crystallizing proteins in microgravity. Results also confirmed that a solubility enhancer used in the drug is radiation resistant and its quality was not affected by microgravity and launch conditions.

Evaluating postflight task performance

Immediately after returning from the International Space Station and for up to one week, astronauts perform functional tasks in ways similar to patients on Earth who have a loss of inner ear function. This finding suggests that comparing data from these patients and astronauts could provide insight into the role of the balance and sensory systems in task performance during critical parts of a mission such as landing on the Moon or Mars.   

Spaceflight causes changes to the balance (vestibular) and sensory systems that can lead to symptoms such as disorientation and impaired locomotion. Standard Measures collects a set of data, including tests of sensorimotor function, related to human spaceflight risks from astronauts before, during, and after missions to help characterize how people adapt to living and working in space.

In an effort to learn more about astronaut health and the effects of space on the human body, NASA is conducting a new experiment aboard the International Space Station to speed up the detection of antibiotic-resistant bacteria, thus improving the health safety not only of astronauts but patients back on Earth.

Infections caused by antibiotic-resistant bacteria can be difficult or impossible to treat, making antibiotic resistance a leading cause of death worldwide and a global health concern.

Future astronauts visiting the Moon or Mars will need to rely on a pre-determined supply of antibiotics in case of illness. Ensuring those antibiotics remain effective is an important safety measure for future missions.

The Genomic Enumeration of Antibiotic Resistance in Space (GEARS) experiment, which is managed by NASA’s Ames Research Center in California’s Silicon Valley, involves astronauts swabbing interior surfaces across the space station and testing those samples for evidence of antibiotic-resistant bacteria, and in particular Enterococcus faecalis, a type of bacteria commonly found in the human body. The experiment is the first step in a series of work that seeks to better understand how organisms grow in a space environment, and how those similarities and differences might help improve research back on Earth.

“Enterococcus is a type of organism that’s been with us since our ancestors crawled out of the ocean, and is a core member of the human gut,” said Christopher Carr, assistant professor at the Georgia Institute of Technology and co-principal investigator of GEARS. “It’s able to survive inside and outside of its host, which has allowed it to become the second highest leading cause of hospital-acquired infections. We want to understand how this type of organism is adapting to the space environment.”

The GEARS experiment seeks to improve the detection and identification of these bacteria, building on existing efforts to understand what organisms grow on the station’s surfaces.

“We’ve been monitoring the surfaces of the space station since 2000, but this experiment will give us insight beyond the identities of present organisms, which is currently all that is used for risk assessment,” said Sarah Wallace, a microbiologist at NASA’s Johnson Space Center in Houston and co-principal investigator of GEARS. “With the station orbiting close to Earth, it’s a low-risk space to evaluate and learn more about the frequency of this bacteria and how it responds to the space environment so we can apply this understanding to missions to the Moon and Mars, where resupplies are more complex.”

Over the next year, astronauts will swab parts of the station and analyze samples by adding an antibiotic to the medium in which the samples will grow. The results will reveal where this and other resistant bacteria are growing and whether they can persist or spread across the station.

The experiment was originally launched to the ISS on the 30^th SpaceX commercial resupply services (CRS) mission in March 2024, and the first round of GEARS testing turned up surprising results: very few resistant bacteria colonies, none of which were E. faecalis. This bodes well for the threat of antibiotic resistance in space.

“There was some cleaning done before swabbing the station, which may have removed some bacteria,” said Carr. To better understand how and where risky bacteria may live, the astronauts paused some cleaning before the second round of swabbing.

“We want the astronauts to have a clean environment, but we also want to test those high-touch areas, so they intentionally and briefly avoided cleaning some areas so we can understand how bacteria may grow or spread on the station.”

This experiment is the first study to perform metagenomic sequencing in space, a method that analyzes all the genetic material in a sample to identify and characterize all organisms that are present, an important research and medical diagnostic capability for future deep space missions.

The GEARS team hopes to create a rapid workflow to analyze bacteria samples, reducing the time between swabbing and test results from days to hours. That workflow could be applied in hospitals and make a huge impact when treating hospital-acquired infections from antibiotic-resistant microbes.

The result could save lives – more than 35,000 people die each year as a result of antibiotic-resistant infections. The issue is personal to Wallace, who lost a family member to a hospital-acquired infection.

“It’s not that uncommon: so many people have experienced this kind of loss,” said Wallace. “A method to give an answer in a matter of hours is huge and profound. It’s my job to keep the crew healthy, but we’re also passionate about bringing that work back down to Earth. I hope we can shine a light on rapidly analyzing bacteria: if we can do this in space, we can do it on Earth, too.”

Genomic Enumeration of Antibiotic Resistance in Space (GEARS) was funded by the Biological and Physical Sciences Space Biology Program, with pioneering funding and support from the Mars Campaign office.

Editor’s note: NASA is rescheduling its upcoming Expedition 73 mission overview briefing and crew news conference originally planned on Monday, Feb. 24. The mission overview briefing now is anticipated to follow NASA’s Crew-10 flight readiness review on Friday, March 7, and the crew news conference will follow the arrival of Crew-10 to the agency’s Kennedy Space Center in Florida. NASA astronaut Jonny Kim will be available on Tuesday, March 18, for limited virtual interviews prior to launch. NASA will share more information on the updated dates and times in the coming days.

Editor’s note: This advisory was updated on Feb. 20, 2025, to reflect an update in participants for the overview news conference.

NASA and its partners will discuss the upcoming Expedition 73 mission aboard the International Space Station during a pair of news conferences on Monday, Feb. 24, from the agency’s Johnson Space Center in Houston.

Mission leadership will participate in an overview news conference at 2 p.m. EST live on NASA+, covering preparations for NASA’s SpaceX Crew-10 launch in March and the agency’s crew member rotation launch on Soyuz in April. Learn how to watch NASA content through a variety of platforms, including social media.

NASA also will host a crew news conference at 4 p.m. and provide coverage on NASA+, followed by individual crew member interviews beginning at 5 p.m. This is the final media opportunity with Crew-10 before the crew members travel to NASA’s Kennedy Space Center in Florida for launch.

The Crew-10 mission, targeted to launch Wednesday, March 12, will carry NASA astronauts Anne McClain and Nichole Ayers, JAXA (Japan Aerospace Exploration Agency) astronaut Takuya Onishi, and Roscosmos cosmonaut Kirill Peskov to the orbiting laboratory.

NASA astronaut Jonny Kim, scheduled to launch to the space station on the Soyuz MS-27 spacecraft no earlier than April 8, also will participate in the crew briefing and interviews. Kim will be available again on Tuesday, March 18, for limited virtual interviews prior to launch. NASA will provide additional details on that opportunity when available.

For the Crew-10 mission, a SpaceX Falcon 9 rocket and Dragon spacecraft will launch from Launch Complex 39A at NASA Kennedy. The three-person crew of Soyuz MS-27, including Kim and Roscosmos cosmonauts Sergey Ryzhikov and Alexey Zubritsky, will launch from the Baikonur Cosmodrome in Kazakhstan.

United States-based media seeking to attend in person must contact the NASA Johnson newsroom no later than 5 p.m. on Friday, Feb. 21, at 281-483-5111 or at jsccommu@mail.nasa.gov. U.S. and international media interested in participating by phone must contact NASA Johnson by 9:45 a.m. the day of the event.

U.S. and international media seeking remote interviews with the crew must submit requests to the NASA Johnson newsroom by 5 p.m. on Feb. 21. A copy of NASA’s media accreditation policy is available online.

Briefing participants include (all times Eastern and subject to change based on real-time operations):

2 p.m.: Expedition 73 Overview News Conference

• Ken Bowersox, associate administrator, Space Operations Mission Directorate at NASA Headquarters in Washington

• Steve Stich, manager, NASA’s Commercial Crew Program, NASA Kennedy
• Dana Weigel, manager, NASA’s International Space Station Program, NASA Johnson
• William Gerstenmaier, vice president, Build & Flight Reliability, SpaceX
• Mayumi Matsuura, vice president and director general, Human Spaceflight Technology Directorate, JAXA

4 p.m.: Expedition 73 Crew News Conference

• Jonny Kim, Soyuz MS-27 flight engineer, NASA
• Anne McClain, Crew-10 spacecraft commander, NASA
• Nichole Ayers, Crew-10 pilot, NASA
• Takuya Onishi, Crew-10 mission specialist, JAXA
• Kirill Peskov, Crew-10 mission specialist, Roscosmos

5 p.m.: Crew Individual Interview Opportunities

• Crew-10 members and Kim available for a limited number of interviews

Kim is making his first spaceflight after selection as part of the 2017 NASA astronaut class. A native of Los Angeles, Kim is a U.S. Navy lieutenant commander and dual designated naval aviator and flight surgeon. Kim also served as an enlisted Navy SEAL. He holds a bachelor’s degree in Mathematics from the University of San Diego and a medical degree from Harvard Medical School in Boston. He completed his internship with the Harvard Affiliated Emergency Medicine Residency at Massachusetts General Hospital and Brigham and Women’s Hospital. After completing the initial astronaut candidate training, Kim supported mission and crew operations in various roles, including the Expedition 65 lead operations officer, T-38 operations liaison, and space station capcom chief engineer. Follow @jonnykimusa on X and @jonnykimusa on Instagram.

Selected by NASA as an astronaut in 2013, this will be McClain’s second spaceflight. A colonel in the U.S. Army, she earned her bachelor’s degree in Mechanical Engineering from the U.S. Military Academy at West Point, New York, and holds master’s degrees in Aerospace Engineering, International Security, and Strategic Studies. The Spokane, Washington, native was an instructor pilot in the OH-58D Kiowa Warrior helicopter and is a graduate of the U.S. Naval Test Pilot School in Patuxent River, Maryland. McClain has more than 2,300 flight hours in 24 rotary and fixed-wing aircraft, including more than 800 in combat, and was a member of the U.S. Women’s National Rugby Team. On her first spaceflight, McClain spent 204 days as a flight engineer during Expeditions 58 and 59, and completed two spacewalks, totaling 13 hours and 8 minutes. Since then, she has served in various roles, including branch chief and space station assistant to the chief of NASA’s Astronaut Office. Follow @astroannimal on X and @astro_annimal on Instagram.

The Crew-10 mission will be the first spaceflight for Ayers, who was selected as a NASA astronaut in 2021. Ayers is a major in the U.S. Air Force and the first member of NASA’s 2021 astronaut class named to a crew. The Colorado native graduated from the Air Force Academy in Colorado Springs with a bachelor’s degree in Mathematics and a minor in Russian, where she was a member of the academy’s varsity volleyball team. She later earned a master’s in Computational and Applied Mathematics from Rice University in Houston. Ayers served as an instructor pilot and mission commander in the T-38 ADAIR and F-22 Raptor, leading multinational and multiservice missions worldwide. She has more than 1,400 total flight hours, including more than 200 in combat. Follow @astro_ayers on X and @astro_ayers on Instagram.

With 113 days in space, this mission also will mark Onishi’s second trip to the space station. After being selected as an astronaut by JAXA in 2009, he flew as a flight engineer for Expeditions 48 and 49, becoming the first Japanese astronaut to robotically capture the Cygnus spacecraft. He also constructed a new experimental environment aboard Kibo, the station’s Japanese experiment module. After his first spaceflight, Onishi became certified as a JAXA flight director, leading the team responsible for operating Kibo from JAXA Mission Control in Tsukuba, Japan. He holds a bachelor’s degree in Aeronautics and Astronautics from the University of Tokyo, and was a pilot for All Nippon Airways, flying more than 3,700 flight hours in the Boeing 767. Follow astro_onishi on X.

The Crew-10 mission will also be Peskov’s first spaceflight. Before his selection as a cosmonaut in 2018, he earned a degree in Engineering from the Ulyanovsk Civil Aviation School and was a co-pilot on the Boeing 757 and 767 aircraft for airlines Nordwind and Ikar. Assigned as a test cosmonaut in 2020, he has additional experience in skydiving, zero-gravity training, scuba diving, and wilderness survival.

Learn more about how NASA innovates for the benefit of humanity through NASA’s Commercial Crew Program at:

https://www.nasa.gov/commercialcrew

-end-

Joshua Finch / Jimi Russell
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / james.j.russell@nasa.gov

Kenna Pell / Sandra Jones
Johnson Space Center, Houston
281-483-5111
kenna.m.pell@nasa.gov / sandra.p.jones@nasa.gov

The 2024 Annual Highlights of Results from the International Space Station is now available. This new edition contains updated bibliometric analyses, a list of all the publications documented in fiscal year 2024, and synopses of the most recent and recognized scientific findings from investigations conducted on the space station. These investigations are sponsored by NASA and all international partners – CSA (Canadian Space Agency), ESA (European Space Agency), JAXA (Japan Aerospace Exploration Agency), and the State Space Corporation Roscosmos (Roscosmos) – for the advancement of science, technology, and education.

Between Oct. 1, 2023, and Sept. 30, 2024, more than 350 publications were reported. With approximately 40% of the research produced in collaboration between more than two countries and almost 80% of the high-impact studies published in the past seven years, station has continued to generate compelling and influential science above national and global standards since 2010.

The results achieved from station research provide insights that advance the commercialization of space and benefit humankind.

Some of the findings presented in this edition include:

• Improved machine learning algorithms to detect space debris (Italian Space Agency, Roscosmos, ESA)
• Visuospatial processing before and after spaceflight (CSA)
• Metabolic changes during fasting intervals in astronauts (ESA)
• Vapor bubble production for the improvement of thermal systems (NASA)
• Immobilization of particles for the development of optical materials (JAXA)
• Maintained function of cardiac 3D stem cells after weeks of exposure to space (NASA)

The content in the Annual Highlights of Results from the International Space Station has been reviewed and approved by the International Space Station Program Science Forum, a team of scientists and administrators representing NASA and international partners that are dedicated to planning, improving, and communicating the research operated on the space station.

[See the list of Station Research Results publications here and find the current edition of the Annual Highlights of Results here.]  

Modeling properties of thunderstorm discharges

Researchers report detailed physical properties of different types of corona discharges, including single- and multi-pulse blue discharges linked to powerful but short-lived electrical bursts near the tops of clouds. These details provide a reference for further investigation into the physical mechanisms behind these discharges and their role in the initiation of lightning, an important problem in lightning physics.

An ESA (European Space Agency) instrument used to study thunderstorms, Atmosphere-Space Interactions Monitor (ASIM) provides insights into their role in Earth’s atmosphere and climate, including mechanisms behind the creation of lightning. Understanding how thunderstorms and lightning disturb the upper atmosphere could improve atmospheric models along with climate and weather predictions. These high-altitude discharges also affect aircraft and spacecraft safety.

Evaluating effects of climate change on oceans

Researchers conclude that the space station’s ECOSTRESS instrument yields highly accurate sea surface temperature data. Given the instrument’s global coverage and high spatial resolution, these data have potential use in studies of biological and physical oceanography to evaluate regional and local effects of climate change.

ECOSTRESS resolves oceanographic features not detectable in imagery from NOAA’s Visible Infrared Imaging Radiometer Suite satellite, and has open-ocean coverage, unlike Landsat. Satellites are a fundamental tool to measure sea surface temperatures, which are rising across all oceans due to atmospheric warming induced by climate change.

Describing a gamma ray burst

Researchers report detailed observations and analysis of emissions from an exceptionally bright gamma ray burst (GRB), 210619B, detected by the station’s ASIM and other satellite and ground-based instruments. These observations could be useful in determining various properties of GRBs and how they change during different phases.

Believed to be generated by the collapse of massive stars, GRBs are the brightest, most explosive transient electromagnetic events in the universe. ASIM can observe thunderstorm discharges difficult to observe from the ground. It has a mode where a detected event triggers observation and onboard storage of data.

Science in Space: February 2025

February was first proclaimed as American Heart Month in 1964. Since then, its 28 (or 29) days have served as an opportunity to encourage people to focus on their cardiovascular health.

The International Space Station serves as a platform for a variety of ongoing research on human health, including how different body systems adapt to weightlessness. This research includes assessing cardiovascular health in astronauts during and after spaceflight and other studies using models of the cardiovascular system, such as tissue cultures. The goal of this work is to help promote heart health for humans in space and everyone on Earth. For this Heart Month, here is a look at some of this spaceflight research

Building a better heart model

Microgravity exposure is known to cause changes in cardiovascular function. Engineered Heart Tissues assessed these changes using 3D cultured cardiac tissues that model the behavior of actual heart tissues better than traditional cell cultures. When exposed to weightlessness, these “heart-on-a-chip” cells behaved in a manner similar to aging on Earth. This finding suggests that these engineered tissues can be used to investigate the effects of space radiation and long-duration spaceflight on cardiac function. Engineered tissues also could support development of measures to help protect crew members during a mission to Mars. Advanced 3D culture methodology may inform development of strategies to prevent and treat cardiac diseases on Earth as well.

Private astronaut heart health

For decades, human research in space has focused on professional and government-agency astronauts, but commercial spaceflight opportunities now allow more people to participate in microgravity research. Cardioprotection Ax-1 analyzed cardiovascular and general health in private astronauts on the 17-day Axiom-1 mission.

The study found that 14 health biomarkers related to cardiac, liver, and kidney health remained within normal ranges during the mission, suggesting that spaceflight did not significantly affect the health of the astronaut subjects. This study paves the way for monitoring and studying the effects of spaceflight on private astronauts and developing health management plans for commercial space providers.

Better measurements for better health

Vascular Echo, an investigation from CSA (Canadian Space Agency), examined blood vessels and the heart using a variety of tools, including ultrasound. A published study suggests that 3D imaging technology might better measure cardiac and vascular anatomy than the 2D system routinely used on the space station. The research team also developed a probe for the ultrasound device that better directs the beam, making it possible for someone who is not an expert in sonography to take precise measurements. This technology could help astronauts monitor heart health and treat cardiovascular issues on a long-duration mission to the Moon or Mars. The technology also could help patients on Earth who live in remote locations, where an ultrasound operator may not always be available.

Long-term heart health in space

As part of exploring ways to keep astronauts healthy on missions to the Moon and Mars, NASA is conducting a suite of space station studies called CIPHER that looks at the effects of spaceflight lasting up to a year. One CIPHER study, Vascular Calcium, examines whether calcium lost from bone during spaceflight might deposit in the arteries, increasing vessel stiffness and contributing to increased risk of future cardiovascular disease. Astronaut volunteers provide blood and urine samples and undergo ultrasound and high-resolution scans of their bones and arteries for this investigation. Another CIPHER study, Coronary Responses, uses advanced imaging tests to measure heart and artery response to spaceflight.

These studies will help scientists determine whether spaceflight accelerates narrowing and stiffening of the arteries, known as atherosclerosis, or increases the risk of atrial fibrillation, a rapid and irregular heartbeat seen in middle-aged adults. This work also could help identify potential biomarkers and early warning indicators of cardiovascular disease.

Melissa Gaskill

International Space Station Research Communications Team

Johnson Space Center

In an effort to learn more about astronaut health and the effects of space on the human body, NASA is conducting a new experiment aboard the International Space Station to speed up the detection of antibiotic-resistant bacteria, thus improving the health safety not only of astronauts but patients back on Earth.

Infections caused by antibiotic-resistant bacteria can be difficult or impossible to treat, making antibiotic resistance a leading cause of death worldwide and a global health concern.

Future astronauts visiting the Moon or Mars will need to rely on a pre-determined supply of antibiotics in case of illness. Ensuring those antibiotics remain effective is an important safety measure for future missions.

The Genomic Enumeration of Antibiotic Resistance in Space (GEARS) experiment, which is managed by NASA’s Ames Research Center in California’s Silicon Valley, involves astronauts swabbing interior surfaces across the space station and testing those samples for evidence of antibiotic-resistant bacteria, and in particular Enterococcus faecalis, a type of bacteria commonly found in the human body. The experiment is the first step in a series of work that seeks to better understand how organisms grow in a space environment, and how those similarities and differences might help improve research back on Earth.

“Enterococcus is a type of organism that’s been with us since our ancestors crawled out of the ocean, and is a core member of the human gut,” said Christopher Carr, assistant professor at the Georgia Institute of Technology and co-principal investigator of GEARS. “It’s able to survive inside and outside of its host, which has allowed it to become the second highest leading cause of hospital-acquired infections. We want to understand how this type of organism is adapting to the space environment.”

The GEARS experiment seeks to improve the detection and identification of these bacteria, building on existing efforts to understand what organisms grow on the station’s surfaces.

“We’ve been monitoring the surfaces of the space station since 2000, but this experiment will give us insight beyond the identities of present organisms, which is currently all that is used for risk assessment,” said Sarah Wallace, a microbiologist at NASA’s Johnson Space Center in Houston and co-principal investigator of GEARS. “With the station orbiting close to Earth, it’s a low-risk space to evaluate and learn more about the frequency of this bacteria and how it responds to the space environment so we can apply this understanding to missions to the Moon and Mars, where resupplies are more complex.”

Over the next year, astronauts will swab parts of the station and analyze samples by adding an antibiotic to the medium in which the samples will grow. The results will reveal where this and other resistant bacteria are growing and whether they can persist or spread across the station.

The experiment was originally launched to the ISS on the 30^th SpaceX commercial resupply services (CRS) mission in March 2024, and the first round of GEARS testing turned up surprising results: very few resistant bacteria colonies, none of which were E. faecalis. This bodes well for the threat of antibiotic resistance in space.

“There was some cleaning done before swabbing the station, which may have removed some bacteria,” said Carr. To better understand how and where risky bacteria may live, the astronauts paused some cleaning before the second round of swabbing.

“We want the astronauts to have a clean environment, but we also want to test those high-touch areas, so they intentionally and briefly avoided cleaning some areas so we can understand how bacteria may grow or spread on the station.”

This experiment is the first study to perform metagenomic sequencing in space, a method that analyzes all the genetic material in a sample to identify and characterize all organisms that are present, an important research and medical diagnostic capability for future deep space missions.

The GEARS team hopes to create a rapid workflow to analyze bacteria samples, reducing the time between swabbing and test results from days to hours. That workflow could be applied in hospitals and make a huge impact when treating hospital-acquired infections from antibiotic-resistant microbes.

The result could save lives – more than 35,000 people die each year as a result of antibiotic-resistant infections. The issue is personal to Wallace, who lost a family member to a hospital-acquired infection.

“It’s not that uncommon: so many people have experienced this kind of loss,” said Wallace. “A method to give an answer in a matter of hours is huge and profound. It’s my job to keep the crew healthy, but we’re also passionate about bringing that work back down to Earth. I hope we can shine a light on rapidly analyzing bacteria: if we can do this in space, we can do it on Earth, too.”

Genomic Enumeration of Antibiotic Resistance in Space (GEARS) was funded by the Biological and Physical Sciences Space Biology Program, with pioneering funding and support from the Mars Campaign office.

The latest edition of NASA’s Spinoff publication, which highlights the successful transfer of agency technology to the commercial sector, is now available online.

For nearly 25 years, NASA has supported crew working in low Earth orbit to learn about the space environment and perform research to advance deep space exploration. Astronauts aboard the International Space Station have learned a wealth of lessons and tried out a host of new technologies. This work leads to ongoing innovations benefiting people on Earth that are featured in NASA’s annual publication.  

“The work we do in space has resulted in navigational technologies, lifesaving medical advancements, and enhanced software systems that continue to benefit our lives on Earth,” said Clayton Turner, associate administrator, Space Technology Mission Directorate at NASA Headquarters in Washington. “Technologies developed today don’t just make life on our home planet easier – they pave the way to a sustained presence on the Moon and future missions to Mars.” 

The Spinoff 2025 publication features more than 40 commercial infusions of NASA technologies including: 

• A platform enabling commercial industry to perform science on the space station, including the growth of higher-quality human heart tissue, knee cartilage, and pharmaceutical crystals that can be grown on Earth to develop new medical treatments.  
• An electrostatic sprayer technology to water plants without the help of gravity and now used in sanitation, agriculture, and food safety.  
• “Antigravity” treadmills helping people with a variety of conditions run or walk for exercise, stemming from efforts to improve astronauts’ fitness in the weightlessness of space.  
• Nutritional supplements originally intended to keep astronauts fit and mitigate the health hazards of a long stay in space.  

As NASA continues advancing technology and research in low Earth orbit to establish a sustained presence at the Moon, upcoming lunar missions are already spinning off technologies on Earth. For example, Spinoff 2025 features a company that invented technology for 3D printing buildings on the Moon that is now using it to print large structures on Earth. Another group of researchers studying how to grow lunar buildings from fungus is now selling specially grown mushrooms and plans to build homes on Earth using the same concept.  

Spinoffs produce innovative technologies with commercial applications for the benefit of all. Other highlights of Spinoff 2025 include quality control on assembly lines inspired by artificial intelligence developed to help rovers navigate Mars, innovations in origami based on math for lasers and optical computing, and companies that will help lead the way to hydrogen-based energy building on NASA’s foundation of using liquid hydrogen for rocket fuel.  

“I’ve learned it’s almost impossible to predict where space technology will find an application in the commercial market,” said Dan Lockney, Technology Transfer program executive at NASA Headquarters in Washington. “One thing I can say for sure, though, is NASA’s technology will continue to spin off, because it’s our goal to advance our missions and bolster the American economy.”  

This publication also features 20 technologies available for licensing with the potential for commercialization. Check out the “Spinoffs of Tomorrow” section to learn more.

Spinoff is part of NASA’s Space Technology Mission Directorate and its Technology Transfer program. Tech Transfer is charged with finding broad, innovative applications for NASA-developed technology through partnerships and licensing agreements, ensuring agency investments benefit the nation and the world.  

To read the latest issue of Spinoff, visit: 

https://spinoff.nasa.gov

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Jasmine Hopkins
Headquarters, Washington
321-432-4624
jasmine.s.hopkins@nasa.gov

Science in Space: February 2025

February was first proclaimed as American Heart Month in 1964. Since then, its 28 (or 29) days have served as an opportunity to encourage people to focus on their cardiovascular health.

The International Space Station serves as a platform for a variety of ongoing research on human health, including how different body systems adapt to weightlessness. This research includes assessing cardiovascular health in astronauts during and after spaceflight and other studies using models of the cardiovascular system, such as tissue cultures. The goal of this work is to help promote heart health for humans in space and everyone on Earth. For this Heart Month, here is a look at some of this spaceflight research

Building a better heart model

Microgravity exposure is known to cause changes in cardiovascular function. Engineered Heart Tissues assessed these changes using 3D cultured cardiac tissues that model the behavior of actual heart tissues better than traditional cell cultures. When exposed to weightlessness, these “heart-on-a-chip” cells behaved in a manner similar to aging on Earth. This finding suggests that these engineered tissues can be used to investigate the effects of space radiation and long-duration spaceflight on cardiac function. Engineered tissues also could support development of measures to help protect crew members during a mission to Mars. Advanced 3D culture methodology may inform development of strategies to prevent and treat cardiac diseases on Earth as well.

Private astronaut heart health

For decades, human research in space has focused on professional and government-agency astronauts, but commercial spaceflight opportunities now allow more people to participate in microgravity research. Cardioprotection Ax-1 analyzed cardiovascular and general health in private astronauts on the 17-day Axiom-1 mission.

The study found that 14 health biomarkers related to cardiac, liver, and kidney health remained within normal ranges during the mission, suggesting that spaceflight did not significantly affect the health of the astronaut subjects. This study paves the way for monitoring and studying the effects of spaceflight on private astronauts and developing health management plans for commercial space providers.

Better measurements for better health

Vascular Echo, an investigation from CSA (Canadian Space Agency), examined blood vessels and the heart using a variety of tools, including ultrasound. A published study suggests that 3D imaging technology might better measure cardiac and vascular anatomy than the 2D system routinely used on the space station. The research team also developed a probe for the ultrasound device that better directs the beam, making it possible for someone who is not an expert in sonography to take precise measurements. This technology could help astronauts monitor heart health and treat cardiovascular issues on a long-duration mission to the Moon or Mars. The technology also could help patients on Earth who live in remote locations, where an ultrasound operator may not always be available.

Long-term heart health in space

As part of exploring ways to keep astronauts healthy on missions to the Moon and Mars, NASA is conducting a suite of space station studies called CIPHER that looks at the effects of spaceflight lasting up to a year. One CIPHER study, Vascular Calcium, examines whether calcium lost from bone during spaceflight might deposit in the arteries, increasing vessel stiffness and contributing to increased risk of future cardiovascular disease. Astronaut volunteers provide blood and urine samples and undergo ultrasound and high-resolution scans of their bones and arteries for this investigation. Another CIPHER study, Coronary Responses, uses advanced imaging tests to measure heart and artery response to spaceflight.

These studies will help scientists determine whether spaceflight accelerates narrowing and stiffening of the arteries, known as atherosclerosis, or increases the risk of atrial fibrillation, a rapid and irregular heartbeat seen in middle-aged adults. This work also could help identify potential biomarkers and early warning indicators of cardiovascular disease.

Melissa Gaskill

International Space Station Research Communications Team

Johnson Space Center

Students from the Thomas Edison EnergySmart Charter School in Somerset, New Jersey, will have the chance to connect with NASA astronaut Nick Hague as he answers prerecorded science, technology, engineering, and mathematics (STEM) related questions from aboard the International Space Station.

Watch the 20-minute space-to-Earth call at 11:10 a.m. EST on Tuesday, Feb. 11, on NASA+ and learn how to watch NASA content on various platforms, including social media.

Media interested in covering the event must RSVP by 5 p.m., Thursday, Feb. 6, to Jeanette Allison at: oyildiz@energysmartschool.org or 732-412-7643.

For more than 24 years, astronauts have continuously lived and worked aboard the space station, testing technologies, performing science, and developing skills needed to explore farther from Earth. Astronauts aboard the orbiting laboratory communicate with NASA’s Mission Control Center in Houston 24 hours a day through SCaN’s (Space Communications and Navigation) Near Space Network.

Important research and technology investigations taking place aboard the space station benefit people on Earth and lay the groundwork for other agency missions. As part of NASA’s Artemis campaign, the agency will send astronauts to the Moon to prepare for future human exploration of Mars; inspiring Artemis Generation explorers and ensuring the United States continues to lead in space exploration and discovery.

See videos and lesson plans highlighting space station research at:

https://www.nasa.gov/stemonstation

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Abbey Donaldson
Headquarters, Washington
202-358-1600
Abbey.a.donaldson@nasa.gov

Sandra Jones 
Johnson Space Center, Houston
281-483-5111
sandra.p.jones@nasa.gov

Editor’s note: This release was updated on Jan. 31, 2025. Axiom Mission 4 will launch from Florida no earlier than spring 2025.

NASA and its international partners have approved the crew for Axiom Space’s fourth private astronaut mission to the International Space Station, launching from Florida no earlier than spring 2025.

Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space, will command the commercial mission, while ISRO (Indian Space Research Organization) astronaut Shubhanshu Shukla will serve as pilot. The two mission specialists are ESA (European Space Agency) project astronaut Sławosz Uznański-Wiśniewski of Poland and Tibor Kapu of Hungary.

“I am excited to see continued interest and dedication for the private astronaut missions aboard the International Space Station,” said Dana Weigel, manager of NASA’s International Space Station Program at the agency’s Johnson Space Center in Houston. “As NASA looks toward the future of low Earth orbit, private astronaut missions help pave the way and expand access to the unique microgravity environment.”

The Axiom Mission 4, or Ax-4, crew will launch aboard a SpaceX Dragon spacecraft and travel to the space station. Once docked, the private astronauts plan to spend up to 14 days aboard the orbiting laboratory, conducting a mission comprised of science, outreach, and commercial activities. The mission will send the first ISRO astronaut to the station as part of a joint effort between NASA and the Indian space agency. The private mission also carries the first astronauts from Poland and Hungary to stay aboard the space station.

“Working with the talented and diverse Ax-4 crew has been a deeply rewarding experience,” said Whitson. “Witnessing their selfless dedication and commitment to expanding horizons and creating opportunities for their nations in space exploration is truly remarkable. Each crew member brings unique strengths and perspectives, making our mission not just a scientific endeavor, but a testament to human ingenuity and teamwork. The importance of our mission is about pushing the limits of what we can achieve together and inspiring future generations to dream bigger and reach farther.”

The first private astronaut mission to the station, Axiom Mission 1, lifted off in April 2022 for a 17-day mission aboard the orbiting laboratory. The second private astronaut mission to the station, Axiom Mission 2, also was commanded by Whitson and launched in May 2023 with four private astronauts who spent eight days in orbit. The most recent private astronaut mission, Axiom Mission 3, launched in January 2024; the crew spent 18 days docked to the space station.

The International Space Station is a convergence of science, technology, and human innovation that enables research not possible on Earth. For more than 24 years, NASA has supported a continuous human presence aboard the orbiting laboratory, through which astronauts have learned to live and work in space for extended periods of time.

The space station is a springboard for developing a low Earth economy. NASA’s goal is to achieve a strong economy in low Earth orbit where the agency can purchase services as one of many customers to meet its science and research objectives in microgravity. NASA’s commercial strategy for low Earth orbit will provide the government with reliable and safe services at a lower cost, enabling the agency to focus on Artemis missions to the Moon in preparation for Mars while also continuing to use low Earth orbit as a training and proving ground for those deep space missions. 

Learn more about NASA’s commercial space strategy at:

https://www.nasa.gov/commercial-space

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Josh Finch / Claire O’Shea
Headquarters, Washington
202-358-1100
joshua.a.finch@nasa.gov / claire.a.o’shea@nasa.gov

Anna Schneider
Johnson Space Center, Houston
281-483-5111
anna.c.schneider@nasa.gov

Alexis DeJarnette
Axiom Space
850-368-9446
alexis@axiomspace.com

Jan. 24, 2025

NASA’s NICER Continues Science Operations Post Repair

NASA crew aboard the International Space Station installed patches to the agency’s NICER (Neutron star Interior Composition Explorer) mission during a spacewalk on Jan. 16. NICER, an X-ray telescope perched near the station’s starboard solar array, resumed science operations later the same day.

The patches cover areas of NICER’s thermal shields where damage was discovered in May 2023. These thin filters block sunlight while allowing X-rays to pass through. After the discovery, the NICER team restricted their observations during the station’s daytime to avoid overwhelming the mission’s sensitive detectors. Nighttime observations were unaffected, and the team was able to continue collecting data for the science community to make groundbreaking measurements using the instrument’s full capabilities.

The repair went according to plan. Data since collected shows the detectors behind the patched areas are performing better than before during station night, and the overall level of sunlight inside NICER during the daytime is reduced substantially.

While NICER experiences less interference from sunlight than before, after analyzing initial data, the team has determined the telescope still experiences more interference than expected. The installed patches cover areas of known damage identified using astronomical observations and from photos taken by both external robotic cameras and astronauts inside the space station. Measurements collected since the repair and close-up, high-resolution photos obtained during the spacewalk are providing new information that may point the way toward further daytime data collection.

In the meantime, NICER continues operations with its full measurement capabilities during orbit night to enable further trailblazing discoveries in time domain and multimessenger astrophysics.

Media contact: Alise Fisher, NASA Headquarters / Claire Andreoli, NASA Goddard

June 8, 2023

Sunlight ‘Leak’ Impacting NASA’s NICER Telescope, Science Continues

On Tuesday, May 22, NASA’s NICER (Neutron Star Interior Composition Explorer), an X-ray telescope on the International Space Station, developed a “light leak,” in which unwanted sunlight enters the instrument. While analyzing incoming data since then, the team identified an impact to daytime observations. Nighttime observations seem to be unaffected.

The team suspects that at least one of the thin thermal shields on NICER’s 56 X-ray Concentrators has been damaged, allowing sunlight to reach its sensitive detectors.

To mitigate the effects on measurements, the NICER team has limited daytime observations to objects far away from the Sun’s position in the sky. The team has also updated commands to NICER that automatically lower its sensitivity during the orbital day to reduce the effects from sunlight contamination. The team is evaluating these changes and assessing additional measures to reduce the impact on science observations.

To date, more than 300 scientific papers have used NICER observations, and the team is confident that NICER will continue to produce world-class science.

Media contact: Alise Fisher, NASA Headquarters / Claire Andreoli, NASA Goddard

Insights into metal alloy solidification

Researchers report details of phase and structure in the solidification of metal alloys on the International Space Station, including formation of microstructures. Because these microstructures determine a material’s mechanical properties, this work could support improvements in techniques for producing coatings and additive manufacturing or 3D printing processes.

METCOMP, an ESA (European Space Agency) investigation, studied solidification in microgravity using transparent organic mixtures as stand-ins for metal alloys. Conducting the research in microgravity removed the influence of convection and other effects of gravity. Results help scientists better understand and validate models of solidification mechanisms, enabling better forecasting of microstructures and improving manufacturing processes.

Measuring the height of upper-atmospheric electrical discharges

Researchers determined the height of a blue discharge from a thundercloud using ground-based electric field measurements and space-based optical measurements from Atmosphere-Space Interactions Monitor (ASIM). This finding helps scientists better understand how these high-altitude lightning-related events affect atmospheric chemistry and could help improve atmospheric models and climate and weather predictions.

ESA’s ASIM is an Earth observation facility that studies severe thunderstorms and upper-atmospheric lighting events and their role in the Earth’s atmosphere and climate. Upper-atmospheric lightning, also known as transient luminous events, occurs well above the altitudes of normal lightning and storm clouds. The data collected by ASIM could support research on the statistical properties of many upper atmosphere lightning events, such as comparison of peak intensities of blue and red pulses with reports from lightning detection networks.

Modeling a complex neutron star

Scientists report that they can use modeling of neutron star PSRJ1231−1411’s X-ray pulses to infer its mass and radius and narrow the possible behaviors of the dense matter at its core. This finding provides a better understanding of the composition and structure of these celestial objects, improving models that help answer questions about conditions in the universe.

The Neutron star Interior Composition Explorer provides high-precision measurements of pulses of X-ray radiation from neutron stars. This particular neutron star presented challenges in finding a fit between models and data, possibly due to fundamental issues with its pulse profile. The authors recommend a program of simulations using synthetic data to determine whether there are fundamental issues with this type of pulse profile that could prevent efforts to obtain tighter and more robust constraints.

Science in Space January 2025

At the start of a new year, many people think about making positive changes in their lives, such as improving physical fitness or learning a particular skill. Astronauts on the International Space Station work all year to maintain a high level of performance while adapting to changes in their physical fitness, cognitive ability, sensory perception, and other functions during spaceflight.

Research on the space station looks at how these qualities change in space, the ways those changes affect daily performance, and countermeasures to keep astronauts at their peak.

A current CSA (Canadian Space Agency) investigation, Space Health, assesses the effects of spaceflight on cardiovascular deconditioning. The investigation uses Bio-Monitor, wearable sensors that collect data such as pulse rate, blood pressure, breathing rate, skin temperature, and physical activity levels. Results could support development of an autonomous system to monitor cardiovascular health on future space missions. Similar technology could be used to monitor heart health in people on Earth.

Maintaining muscle fitness

During spaceflight, astronauts lose muscle mass and stiffness, an indication of strength. Astronauts exercise daily to counteract these effects, but monitoring the effectiveness of exercise had been limited to before and after flight due to the lack of technologies appropriate for use in space. The ESA (European Space Agency) Myotones investigation demonstrated that a small, non-invasive device accurately measured muscle stiffness and showed that current countermeasures seem to be effective for most muscle groups. Accurate inflight assessment could help scientists target certain muscles to optimize the effectiveness of exercise programs on future missions. The measuring device also could benefit patients in places on Earth without other means for monitoring.

Keeping a sharp mind

Research suggests that the effects of spaceflight on cognitive performance likely are due to the influence of stressors such as radiation and sleep disruption. Longer missions that increase the exposure to these hazards may change how they affect individuals.

Manual Control used a battery of tests to examine how spaceflight affects cognitive, sensory, and motor function right after landing. The day they return from spaceflight, astronauts demonstrate significant impairments in fine motor control and ability to multitask in simulated flying and driving challenges. Researchers attribute this to subtle physiological changes during spaceflight. Performance recovered once individuals were exposed to a task, suggesting that having crew members conduct simulated tasks right before actual ones could be beneficial. This work helps scientists ensure that crew members can safely land and conduct early operations on the Moon and Mars.

Standard Measures collects a set of physical and mental measurements related to human spaceflight risks, including a cognition test battery, from astronauts before, during, and after missions. Using these data, researchers found that astronauts on 6-month missions demonstrated generally stable cognitive performance with mild changes in certain areas, including processing speed, working memory, attention, and willingness to take risks. The finding provides baseline data that could help identify cognitive changes on future missions and support development of appropriate countermeasures. This research includes the largest sample of professional astronauts published to date.

Evaluating perception

Another function that can be affected by spaceflight is sensory perception, such as the ability to interpret motion, orientation, and distance. We use our visual perception of the height and width of objects around us, for example, to complete tasks such as reaching for an object and deciding whether we can fit through an opening. VECTION, a CSA investigation, found that microgravity had no immediate effect on the ability to perceive the height of an object, indicating that astronauts can safely perform tasks that rely on this judgment soon after they arrive in space. Researchers concluded there is no need for countermeasures but did suggest that space travelers be made aware of late-emerging and potentially long-lasting changes in the ability to perceive object height.

Melissa Gaskill

International Space Station Research Communications Team

Johnson Space Center

Measurements from space support wildfire risk predictions

Researchers demonstrated that data from the International Space Station’s ECOsystem Spaceborne Thermal Radiometer Experiment on Space Station (ECOSTRESS) instrument played a significant role in the ability of machine learning algorithms to predict wildfire susceptibility. This result could help support development of effective strategies for predicting, preventing, monitoring, and managing wildfires.

As the frequency and severity of wildfires increases worldwide, experts need reliable models of fire susceptibility to protect public safety and support natural resource planning and risk management. ECOSTRESS measures evapotranspiration, water use efficiency, and other plant-water dynamics on Earth. Researchers report that its water use efficiency data consistently emerged as the leading factor in predicting wildfires, with evaporative stress and topographic slope data also significant.

Combining instruments provides better emissions data

Scientists found that averaging data from the International Space Station’s OCO‐3 and EMIT external instruments can accurately measure the rate of carbon dioxide emissions from power plants. This work could improve emissions monitoring and help communities respond to climate change.

Carbon dioxide emissions from fossil fuel combustion make up nearly a third of human-caused emissions and are a major contributor to climate change. In many places, though, scientists do not know exactly how much carbon dioxide these sources emit. The Orbiting Carbon Observatory-3 or OCO-3 can quantify emissions over large areas and Earth Surface Mineral Dust Source Investigation data can help determine emissions from individual facilities. The researchers suggest future work continue to investigate the effect of wind conditions on measurements.

Thunderstorm phenomena observed from space

Observations by the International Space Station’s Atmosphere-Space Interactions Monitor (ASIM) instrument during a tropical cyclone in 2019 provide insight into the formation and nature of blue corona discharges often observed at the tops of thunderclouds. A better understanding of such processes in Earth’s upper atmosphere could improve atmospheric models and weather and climate predictions.

Scientists do not fully understand the conditions that lead to formation of blue corona discharges, bursts of electrical streamers, which are precursors to lightning. Observations from the ground are affected by scattering and absorption in the clouds. ASIM, a facility from ESA (European Space Agency), provides a unique opportunity for observing these high-atmosphere events from space.

NASA astronaut Nick Hague will install patches to the agency’s NICER (Neutron star Interior Composition Explorer) X-ray telescope on the International Space Station as part of a spacewalk scheduled for Jan. 16. Hague, along with astronaut Suni Williams, will also complete other tasks during the outing.

NICER will be the first NASA observatory repaired on-orbit since the last servicing mission for the Hubble Space Telescope in 2009.

Hague and other astronauts, including Don Pettit, who is also currently on the space station, rehearsed the NICER patch procedures in the NBL (Neutral Buoyancy Laboratory), a 6.2-million-gallon indoor pool at NASA’s Johnson Space Center in Houston, in 2024. 

“We use the NBL to mimic, as much as possible, the conditions astronauts will experience while preforming a task during a spacewalk,” said Lucas Widner, a flight controller at KBR and NASA Johnson who ran the NICER NBL sessions. “Most projects outside the station focus on maintenance and upgrades to components like solar panels. It’s been exciting for all of us to be part of getting a science mission back to normal operations.”

From its perch near the space station’s starboard solar array, NICER studies the X-ray sky, including erupting galaxies, black holes, superdense stellar remnants called neutron stars, and even comets in our solar system. 

But in May 2023, NICER developed a “light leak.” Sunlight began entering the telescope through several small, damaged areas in the telescope’s thin thermal shields. During the station’s daytime, the light reaches the X-ray detectors, saturating sensors and interfering with NICER’s measurements of cosmic objects. The mission team altered their daytime observing strategy to mitigate the effect. 

The team also developed a plan to cover the largest areas of damage using wedge-shaped patches. Hague will slide the patches into the telescope’s sunshades and lock them into place. 

“We designed the patches so they could be installed either robotically or by an astronaut,” said Steve Kenyon, NICER’s mechanical engineering lead at NASA’s Goddard Space Flight Center in Greenbelt, Maryland. “They’re installed using a tool called a T-handle that the astronauts are already familiar with.”

The NBL contains life-size mockups of sections of the space station. Under the supervision of a swarm of scuba divers, a pair of astronauts rehearse exiting and returning through an airlock, traversing the outside of the station, and completing tasks. 

For the NICER repair, the NBL team created a full-scale model of NICER and its surroundings near the starboard solar array. Hague, Pettit, and other astronauts practiced taking the patches out of their caddy, inserting them into the sunshades, locking them into place, and verifying they were secure. 

The task took just under an hour each time, which included the time astronauts needed to travel to NICER, set up their tools, survey the telescope for previously undetected damage, complete the repair, and clean up their tools. 

Practice runs also provided opportunities for the astronauts to troubleshoot how to position themselves so they could reach NICER without touching it too often and for flight controllers to identify safety concerns around the repair. 

Being fully submerged in a pool is not the same as being in space, of course, so some issues that arose were “pool-isms.” For example, astronauts sometimes drifted upward while preparing to install the patches in a way unlikely to happen in space. 

Members of the NICER team, including Kenyon and the mission’s principal investigator, Keith Gendreau at NASA Goddard, supported the NBL practice runs. They helped answer questions about the physical aspects of the telescope, as well as science questions from the astronauts and flight controllers. NICER is the leading source of science results on the space station. 

“It was awesome to watch the training sessions and be able to debrief with the astronauts afterward,” Gendreau said. “There isn’t usually a lot of crossover between astrophysics science missions and human spaceflight. NICER will be the first X-ray telescope serviced by astronauts. It’s been an exciting experience, and we’re all looking forward to the spacewalk where it will all come together.”

The NICER telescope is an Astrophysics Mission of Opportunity within NASA’s Explorers Program, which provides frequent flight opportunities for world-class scientific investigations from space utilizing innovative, streamlined, and efficient management approaches within the heliophysics and astrophysics science areas. NASA’s Space Technology Mission Directorate supported the SEXTANT component of the mission, demonstrating pulsar-based spacecraft navigation.

By Jeanette Kazmierczak
NASA’s Goddard Space Flight Center, Greenbelt, Md.

Media Contact:
Claire Andreoli
301-286-1940
claire.andreoli@nasa.gov
NASA’s Goddard Space Flight Center, Greenbelt, Md.

For more than 24 years, NASA has supported a continuous U.S. human presence aboard the International Space Station, advancing scientific knowledge and making research breakthroughs not possible on Earth for the benefit of humanity. The space station is a springboard to NASA’s next great leaps in exploration, including future missions to the Moon under Artemis, and ultimately, human exploration of Mars.

Read more about the groundbreaking work conducted in 2024 aboard the station:

Robot performs remote simulated surgery

On long-duration missions, crew members may need surgical procedures, whether simple stitches or an emergency appendectomy. A small robot successfully performed simulated surgical procedures on the space station in early February 2024 for the Robotic Surgery Tech Demo, using two “hands” to grasp and cut rubber bands simulating tissue. Researchers compare the procedures conducted aboard the station and on Earth to evaluate the effects of microgravity and communication delays between space and ground.

3D metal print in space

On May 30,2024, the ESA (European Space Agency) Metal 3D Printer investigation created a small stainless steel s-curve, the first metal 3D print in space. Crew members on future missions could print metal parts for equipment maintenance, eliminating the need to pack spare parts and tools at launch. This technology also has the potential to improve additive manufacturing on Earth.

Here’s looking at you, Earth

The space station orbits roughly 250 miles above and passes over 90 percent of Earth’s population, providing a unique perspective for photographing the planet. Astronauts have taken more than 5.3 million images of Earth to monitor the planet’s changing landscape. The Expedition 71 crew took over 630,000 images, well above the average of roughly 105,000 for a single mission. This year, images included the April solar eclipse and auroras produced as the Sun’s 11-year activity cycle peaks. Others supported response to over 14 disaster events including hurricanes. In addition, 80,000 images were geolocated using machine learning, improving public search capabilities.

Miles of flawless fibers

From mid-February to mid-March of 2024, the Flawless Space Fibers-1 system produced more than seven miles of optical fiber in space. One draw of more than a half mile of fiber surpassed the prior record of 82 feet for the longest fiber manufactured in space, demonstrating that commercial lengths of fiber can be produced in orbit. Fibers produced in microgravity can be superior to those produced in Earth’s gravity. These fibers are made from ZBLAN, a glass alloy with the potential to provide more than 10 times the transmission capacity of traditional silica-based fibers.

Tell-tale heart

In May 2024, BFF-Cardiac successfully bioprinted a three-dimensional human heart tissue sample using the Redwire BioFabrication Facility. Tissues bioprinted in the microgravity of the space station hold their shape without the use of artificial scaffolds. These bioprinted human heart tissues eventually could be used to create personalized patches for tissue damaged by events such as heart attacks. The tissue sample is undergoing further testing on Earth.

Station-tested radiation technology flown on Artemis I

The Orion spacecraft carried 5,600 passive and 34 active radiation detectors on its Artemis I uncrewed mission around the Moon in November 2022. Some of these devices previously were tested on the space station: HERA (Hybrid Electronic Radiation Assessor), which detects radiation events such as solar flares; the ESA (European Space Agency) Active Dosimeters, a wearable device collecting real-time data on individual radiation doses; and the AstroRad Vest, a garment to protect radiation-sensitive organs and tissues. In 2024, researchers released evaluation of data collected in 2022 by these tools that indicate the Orion spacecraft can protect astronauts on lunar missions from potentially hazardous radiation. The orbiting laboratory remains a valuable platform for testing technology for missions beyond Earth’s orbit.

Record participation in Fifth Robo-Pro Challenge

A record 661 teams and 2,788 applicants from thirteen countries, regions, and organizations participated in the fifth Kibo Robo-Pro Challenge, which wrapped its final round in September. This educational program from JAXA (Japan Aerospace Exploration Agency) has students solve various problems by programming free-flying Astrobee robots aboard the space station. Participants gain hands-on experience with space robot technology and software programming and interact with others from around the world.

Melissa Gaskill
International Space Station Research Communications Team|
Johnson Space Center

In December 2024, five CubeSats deployed into Earth’s orbit from the International Space Station. Among them was LignoSat, a wooden satellite from JAXA (Japanese Aerospace Exploration Agency) that investigates the use of wood in space. Findings could offer a more sustainable alternative to conventional satellites.

A previous experiment aboard station exposed three species of wood to the space environment to help researchers determine the best option for LignoSat. The final design used 10 cm long honoki magnolia wood panels assembled with a Japanese wood-joinery method.

Researchers will use sensors to evaluate strain on the wood and measure its responses to temperature and radiation in space. Geomagnetic levels will also be monitored to determine whether the geomagnetic field can penetrate the body of the wooden satellite and interfere with its technological capabilities. Investigating uses for wood in space could lead to innovative solutions in the future.